Rawle, who wreaked havoc as serial killer Silas in Hollyoaks, will appear in the medical drama early next year – playing a road sweeper with something to hide.
A spokesperson told DS: “We are delighted to be booking the fabulous Jeff Rawle for a weighty guest role in an episode to be transmitted early next year.
“Jeff will play Rory Bishton, a road sweeper with a secret, who finds his double life increasingly difficult to sustain, in an episode which will pique the curiosity and pull the heartstrings.”
Rawle will begin filming with the Birmingham-based soap next week.
As well as his role in Hollyoaks, Rawle is well-known for his parts as Amos Diggory in Harry Potter and the Goblet of Fire and George in Drop the Dead Donkey.